Varroa destructor is an effective vector of Israeli acute paralysis virus in the honeybee, Apis mellifera.

نویسندگان

  • Gennaro Di Prisco
  • Francesco Pennacchio
  • Emilio Caprio
  • Humberto F Boncristiani
  • Jay D Evans
  • Yanping Chen
چکیده

The Israeli acute paralysis virus (IAPV) is a significant marker of honeybee colony collapse disorder (CCD). In the present work, we provide the first evidence that Varroa destructor is IAPV replication-competent and capable of vectoring IAPV in honeybees. The honeybees became infected with IAPV after exposure to Varroa mites that carried the virus. The copy number of IAPV in bees was positively correlated with the density of Varroa mites and time period of exposure to Varroa mites. Further, we showed that the mite-virus association could possibly reduce host immunity and therefore promote elevated levels of virus replication. This study defines an active role of Varroa mites in IAPV transmission and sheds light on the epidemiology of IAPV infection in honeybees.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Virus Infections of Honeybees Apis Mellifera

The health and vigour of honeybee colonies are threatened by numerous parasites (such as Varroa destructor and Nosema spp.) and pathogens, including viruses, bacteria, protozoa. Among honeybee pathogens, viruses are one of the major threats to the health and well-being of honeybees and cause serious concern for researchers and beekeepers. To tone down the threats posed by these invasive organis...

متن کامل

A mathematical model for population dynamics in honeybee colonies infested with Varroa destructor and the Acute Bee Paralysis Virus

We present a simple SIR-Ross-MacDonald like model of the infestation of a honeybee (Apis mellifera) colony by the Acute Bee Paralysis Virus (ABPV), which is transmitted by parasitic varroa mites (Varroa destructor) as vector. This is a four dimensional system of nonlinear ordinary differential equations for the dependent variables healthy and virus infected bees, number of mites in the colony o...

متن کامل

Two novel viruses associated with the Apis mellifera pathogenic mite Varroa destructor

Varroa destructor infestation of Apis mellifera colonies carries and/or promotes replication of honey bee viruses like the Deformed wing virus, the Varroa destructor virus-1, the Acute bee paralysis virus, the Israeli acute bee paralysis virus and the Kashmir bee virus that have been well described and characterized; but viruses exclusively associated with Varroa were not found. To look for vir...

متن کامل

Seasonal prevalence of pathogens and parasites in the savannah honeybee (Apis mellifera scutellata).

The loss of Apis mellifera L. colonies in recent years has, in many regions of the world, been alarmingly high. No single cause has been identified for these losses, but the interactions between several factors (mostly pathogens and parasites) have been held responsible. Work in the Americas on honeybees originating mainly from South Africa indicates that Africanised honeybees are less affected...

متن کامل

Bidirectional Transfer of RNAi between Honey Bee and Varroa destructor: Varroa Gene Silencing Reduces Varroa Population

The mite Varroa destructor is an obligatory ectoparasite of the honey bee (Apis mellifera) and is one of the major threats to apiculture worldwide. We previously reported that honey bees fed on double-stranded RNA (dsRNA) with a sequence homologous to that of the Israeli acute paralysis virus are protected from the viral disease. Here we show that dsRNA ingested by bees is transferred to the Va...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of general virology

دوره 92 Pt 1  شماره 

صفحات  -

تاریخ انتشار 2011